DEFINITIONS & HISTORY: CLEANROOM ORIGINS

These early efforts concentrated on the sterilization of the operating room instruments and dressings, along with the use of surgical masks and gloves. With the basis of cleanroom techniques established by this work, the next major advance was the implementation of mechanical ventilation in the control of bacterial infection.

Although not widely adopted until the end of the Second World War, the use of artificial ventilation, advocated by people such as Florence Nightingale, was seen as early as the Crimean War (1855).

Old photo showing Lister and staff at King's College Hospital.
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